Evaluation of the Effect of Chia (Salvia hispanica) Seeds Extract in modulating Fertility Potential, Injury and Histopathological Alterations Induced by Fenitrothion in Male Rats


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Authors

  • SAMEER ABED MOHAMMED 1Collage of pharmacy, University of Anbar, Anbar, Iraq. 2Department of pharmacy, Alfarabi university college, Al-droa, Baghdad, Iraq. 3Al. Karkh University of Sciences, Baghdad, Iraq. 4Biotechnology Research Center, Al-Nahrain University, Baghdad, Iraq. 5 Department of Biology, Al-Farabi University College of Baghdad, Iraq 6Marine Biology Department, Faculty of Marine Sciences, King Abdulaziz University, Saudi. 7Department of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Author
  • AHMED M 1Collage of pharmacy, University of Anbar, Anbar, Iraq. 2Department of pharmacy, Alfarabi university college, Al-droa, Baghdad, Iraq. 3Al. Karkh University of Sciences, Baghdad, Iraq. 4Biotechnology Research Center, Al-Nahrain University, Baghdad, Iraq. 5 Department of Biology, Al-Farabi University College of Baghdad, Iraq 6Marine Biology Department, Faculty of Marine Sciences, King Abdulaziz University, Saudi. 7Department of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Author
  • AI YASSEN 1Collage of pharmacy, University of Anbar, Anbar, Iraq. 2Department of pharmacy, Alfarabi university college, Al-droa, Baghdad, Iraq. 3Al. Karkh University of Sciences, Baghdad, Iraq. 4Biotechnology Research Center, Al-Nahrain University, Baghdad, Iraq. 5 Department of Biology, Al-Farabi University College of Baghdad, Iraq 6Marine Biology Department, Faculty of Marine Sciences, King Abdulaziz University, Saudi. 7Department of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Author
  • MARWA SALIM ALI 1Collage of pharmacy, University of Anbar, Anbar, Iraq. 2Department of pharmacy, Alfarabi university college, Al-droa, Baghdad, Iraq. 3Al. Karkh University of Sciences, Baghdad, Iraq. 4Biotechnology Research Center, Al-Nahrain University, Baghdad, Iraq. 5 Department of Biology, Al-Farabi University College of Baghdad, Iraq 6Marine Biology Department, Faculty of Marine Sciences, King Abdulaziz University, Saudi. 7Department of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Author
  • AHMED FLAYYIH HASAN 1Collage of pharmacy, University of Anbar, Anbar, Iraq. 2Department of pharmacy, Alfarabi university college, Al-droa, Baghdad, Iraq. 3Al. Karkh University of Sciences, Baghdad, Iraq. 4Biotechnology Research Center, Al-Nahrain University, Baghdad, Iraq. 5 Department of Biology, Al-Farabi University College of Baghdad, Iraq 6Marine Biology Department, Faculty of Marine Sciences, King Abdulaziz University, Saudi. 7Department of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Author
  • HANY M 1Collage of pharmacy, University of Anbar, Anbar, Iraq. 2Department of pharmacy, Alfarabi university college, Al-droa, Baghdad, Iraq. 3Al. Karkh University of Sciences, Baghdad, Iraq. 4Biotechnology Research Center, Al-Nahrain University, Baghdad, Iraq. 5 Department of Biology, Al-Farabi University College of Baghdad, Iraq 6Marine Biology Department, Faculty of Marine Sciences, King Abdulaziz University, Saudi. 7Department of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Author
  • EI WAHSH 1Collage of pharmacy, University of Anbar, Anbar, Iraq. 2Department of pharmacy, Alfarabi university college, Al-droa, Baghdad, Iraq. 3Al. Karkh University of Sciences, Baghdad, Iraq. 4Biotechnology Research Center, Al-Nahrain University, Baghdad, Iraq. 5 Department of Biology, Al-Farabi University College of Baghdad, Iraq 6Marine Biology Department, Faculty of Marine Sciences, King Abdulaziz University, Saudi. 7Department of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Author
  • MOHAMED KORISH 1Collage of pharmacy, University of Anbar, Anbar, Iraq. 2Department of pharmacy, Alfarabi university college, Al-droa, Baghdad, Iraq. 3Al. Karkh University of Sciences, Baghdad, Iraq. 4Biotechnology Research Center, Al-Nahrain University, Baghdad, Iraq. 5 Department of Biology, Al-Farabi University College of Baghdad, Iraq 6Marine Biology Department, Faculty of Marine Sciences, King Abdulaziz University, Saudi. 7Department of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Author

Keywords:

Chia (Salvia hispanica) seeds extract, FSH, Fenitrothion, LH, Testosterone, Sperm count, Rat

Abstract

The study aimed to evaluate the effect of chia seed extract as a protective against fenitrothion toxicity in male rats. Total forty rats were divided into four groups: the first group was the control group (no treatment), the second group was treated with Chia (Salvia hispanica) seeds at a dose of 400 mg/kg body weight daily, the third group was treated with Fenitrothion at a dose of 100 mg/kg body weight, and the fourth group was treated with both Chia (Salvia hispanica) seeds and fenitrothion. Rats were treated orally for three weeks daily. The results showed changes in the concentration of hormones and sperm characteristics in rats treated with fenitrothion compared to the control group. The exposure to fenitrothion has a noticeable toxic effect on rats through measuring some vital indicators. The role of chia seed extract in reducing lipid oxidation and improving the antioxidant defense system has been proven. We conclude from the above that exposure to fenitrothion has a noticeable toxic effect on rats through measuring some vital indicators, The role of chia seed extract in reducing lipid oxidation and improving the antioxidant defense system has been proven

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Published

2026-08-01

Issue

Vol. 46 No. 3 (2025): The Indian Journal of Animal Reproduction

Section

Articles

How to Cite

Evaluation of the Effect of Chia (Salvia hispanica) Seeds Extract in modulating Fertility Potential, Injury and Histopathological Alterations Induced by Fenitrothion in Male Rats. (2026). The Indian Journal of Animal Reproduction, 46(3), 106-112. https://issar.net.in/index.php/issar/article/view/977

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